| ncRNA name | hsa-miR-326 |
| ncRNA Category | miRNA |
| Disease name | age-related cataract |
| Species | Homo sapiens |
| Tissues/Cell_line | human lens epithelial cell line HLE-B3 |
| Methods | transfection, CCK-8 assay, flow cytometry, luciferase activity assay, Western blot |
| Expression pattern | associated |
| Functional description | miR-326 exacerbated but its antagomirs attenuated H2O2-induced apoptosis of HLEC-B3 human lens epithelial cells. miR-326 inhibited FGF1 expression by directly targeting its mRNA 3'-UTR. |
| PubMed ID | 30268497 |
| Year | 2018 |
| Title | MiR-326 antagomir delays the progression of age-related cataract by upregulating FGF1-mediated expression of betaB2-crystallin. |
| Drug-related ncRNA | NO |
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